South Street will be closed from Wednesday, 27th July until Friday, 29th July, for surface repairs.
The road will be closed to all traffic between 8am and 4pm and "No Parking" restrictions will also be in operation in order to allow the works to be completed.
Councillor Craig Browne said "Over the next three years, Cheshire East Council is investing £19m (including £7m this year and then £6m in 2023/24, followed by a further £6m in 2024/25) in its highways repair programme.
"Unfortunately, following a 23% reduction in government funding for road repairs last year, this additional investment is having to be funded through borrowing; however, it is necessary to prevent the further decline of our road network, with the council now facing a £180m backlog of repairs."
He added "Using the additional investment, Level 2 patching works were carried out on Macclesfield Road earlier in the Spring and I am pleased to report that these will be reinforced with top level surface dressing. These works are also due to be carried out over a three day period later this week."
Further patching works to Congleton Road (from the de Trafford Arms to Melrose Way) are planned later this year.